Protection against simian/human immunodeficiency virus (SHIV) 89.6P in macaques after coimmunization with SHIV antigen and IL-15 plasmid

The cell-mediated immune profile induced by a recombinant DNA vaccine was assessed in the simian/HIV (SHIV) and macaque model. The vaccine strategy included coimmunization of a DNA-based vaccine alone or in combination with an optimized plasmid encoding macaque IL-15 (pmacIL-15). We observed strong...

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Detalhes bibliográficos
Main Authors: Boyer, Jean D., Robinson, Tara M., Kutzler, Michele A., Vansant, Gordon, Hokey, David A., Kumar, Sanjeev, Parkinson, Rose, Wu, Ling, Sidhu, Maninder K., Pavlakis, George N., Felber, Barbara K., Brown, Charles, Silvera, Peter, Lewis, Mark G., Monforte, Joseph, Waldmann, Thomas A., Eldridge, John, Weiner, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141831/
https://ncbi.nlm.nih.gov/pubmed/18000037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709198104
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