Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord

The notochord develops from notochord progenitor cells (NPCs) and functions as a major signaling center to regulate trunk and tail development. NPCs are initially specified in the node by Wnt and Nodal signals at the gastrula stage. However, the underlying mechanism that maintains the NPCs throughou...

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Detalhes bibliográficos
Main Authors: Ukita, Kanako, Hirahara, Shino, Oshima, Naoko, Imuta, Yu, Yoshimoto, Aki, Jang, Chuan-Wei, Oginuma, Masayuki, Saga, Yumiko, Behringer, Richard R., Kondoh, Hisato, Sasaki, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757446/
https://ncbi.nlm.nih.gov/pubmed/19720144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2009.08.003
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