Movement of the free catalytic subunit of cAMP-dependent protein kinase into and out of the nucleus can be explained by diffusion.

The catalytic (C) subunit of cyclic AMP (cAMP) dependent protein kinase (PKA) has previously been shown to enter and exit the nucleus of cells when intracellular cAMP is raised and lowered, respectively. To determine the mechanism of nuclear translocation, fluorescently labeled C subunit was injecte...

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Pubblicato in:	Mol Biol Cell
Autori principali:	Harootunian, A T, Adams, S R, Wen, W, Meinkoth, J L, Taylor, S S, Tsien, R Y
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Cell Biology 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8298196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.10.993
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