Movement of the free catalytic subunit of cAMP-dependent protein kinase into and out of the nucleus can be explained by diffusion.

The catalytic (C) subunit of cyclic AMP (cAMP) dependent protein kinase (PKA) has previously been shown to enter and exit the nucleus of cells when intracellular cAMP is raised and lowered, respectively. To determine the mechanism of nuclear translocation, fluorescently labeled C subunit was injecte...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Harootunian, A T, Adams, S R, Wen, W, Meinkoth, J L, Taylor, S S, Tsien, R Y
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8298196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.10.993
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