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The SLAM-Associated Protein (SAP)/Fyn/PKCθ Pathway is Required for Thymocyte-mediated CD4 T Cell Development
MHC class II-expressing double positive thymocytes induce progression of CD4 T cell development, as efficiently as cortical thymic epithelial cells (cTEC). Because double positive thymocytes expressing CD1d select NKT cells, we investigated whether thymocyte-selected CD4 (T-CD4) T cells require the...
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Autori principali: | , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2007
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757291/ https://ncbi.nlm.nih.gov/pubmed/18031696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.10.008 |
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