The SLAM-Associated Protein (SAP)/Fyn/PKCθ Pathway is Required for Thymocyte-mediated CD4 T Cell Development

MHC class II-expressing double positive thymocytes induce progression of CD4 T cell development, as efficiently as cortical thymic epithelial cells (cTEC). Because double positive thymocytes expressing CD1d select NKT cells, we investigated whether thymocyte-selected CD4 (T-CD4) T cells require the...

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Bibliographische Detailangaben
Hauptverfasser: Li, Wei, Sofi, M. Hanief, Rietdijk, Svend, Wang, Ninghai, Terhorst, Cox, Chang, Cheong-Hee
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757291/
https://ncbi.nlm.nih.gov/pubmed/18031696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.10.008
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