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Elevated IL-6 expression in CD4 T cells via PKCθ and NF-κB induces Th2 cytokine production

T helper (Th) cell differentiation is a key event to mount an appropriate immune response. Th1 and Th2 cells produce their signature cytokines IFN-γ and IL-4, respectively. However, as we have reported, CD4 T cells selected by MHC class II-expressing thymocytes (T-CD4) produce both Th1 and Th2 type...

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Detalhes bibliográficos
Main Authors: Sofi, M. Hanief, Li, Wei, Kaplan, Mark H., Chang, Cheong-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757281/
https://ncbi.nlm.nih.gov/pubmed/19181387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.12.014
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