Heterokaryon myotubes with normal mouse and Duchenne nuclei exhibit sarcolemmal dystrophin staining and efficient intracellular free calcium control.

Duchenne and mdx muscle tissues lack dystrophin where it normally interacts with glycoproteins in the sarcolemma. Intracellular free calcium ([Ca2+]i) is elevated in Duchenne and mdx myotubes and is correlated with abnormally active calcium-specific leak channels in dystrophic myotubes. We fused Duc...

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Veröffentlicht in:	Mol Biol Cell
Hauptverfasser:	Denetclaw, W F, Bi, G, Pham, D V, Steinhardt, R A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Cell Biology 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275726/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8257798/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.9.963
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