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The Flexible Motif V of Epstein-Barr Virus Deoxyuridine 5′-Triphosphate Pyrophosphatase Is Essential for Catalysis

Deoxyuridine 5′-triphosphate pyrophosphatases (dUTPases) are ubiquitous enzymes essential for hydrolysis of dUTP, thus preventing its incorporation into DNA. Although Epstein-Barr virus (EBV) dUTPase is monomeric, it has a high degree of similarity with the more frequent trimeric form of the enzyme....

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Hlavní autoři: Freeman, Lucy, Buisson, Marlyse, Tarbouriech, Nicolas, Van der Heyden, Angéline, Labbé, Pierre, Burmeister, Wim P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757230/
https://ncbi.nlm.nih.gov/pubmed/19586911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019315
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