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Dioxin Receptor Deficiency Impairs Angiogenesis by a Mechanism Involving VEGF-A Depletion in the Endothelium and Transforming Growth Factor-β Overexpression in the Stroma

Angiogenesis has key roles in development and in the progression of human diseases such as cancer. Consequently, identifying the novel markers and regulators of angiogenesis is a critical task. The dioxin receptor (AhR) contributes to vascular homeostasis and to the endothelial response to toxins, a...

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Main Authors: Roman, Angel Carlos, Carvajal-Gonzalez, Jose M., Rico-Leo, Eva M., Fernandez-Salguero, Pedro M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757217/
https://ncbi.nlm.nih.gov/pubmed/19617630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.013292
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