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Mechanistic Basis for Differential Inhibition of the F(1)F(o)-ATPase by Aurovertin

The mitochondrial F(1)F(o)-ATPase performs the terminal step of oxidative phosphorylation. Small molecules that modulate this enzyme have been invaluable in helping decipher F(1)F(o)-ATPase structure, function, and mechanism. Aurovertin is an antibiotic that binds to the β subunits in the F(1) domai...

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Detalhes bibliográficos
Main Authors: Johnson, Kathryn M., Swenson, Lara, Opipari, Anthony W., Reuter, Rolf, Zarrabi, Nawid, Fierke, Carol A., Börsch, Michael, Glick, Gary D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757082/
https://ncbi.nlm.nih.gov/pubmed/19462418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21262
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