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Ratiocinative Screen of Eukaryotic Integral Membrane Protein Expression and Solubilization for Structure Determination

Persistent hurdles impede the successful determination of high-resolution crystal structures of eukaryotic integral membrane proteins (IMP). We designed a high-throughput structural genomics oriented pipeline that seeks to minimize effort in uncovering high-quality, responsive non-redundant targets...

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Detalhes bibliográficos
Main Authors: Hays, Franklin A., Roe-Zurz, Zygy, Li, Min, Kelly, Libusha, Gruswitz, Franz, Sali, Andrej, Stroud, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756966/
https://ncbi.nlm.nih.gov/pubmed/19031011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10969-008-9046-7
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