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The Natural Product Honokiol Preferentially Inhibits c-FLIP and Augments Death Receptor-induced Apoptosis

Targeting death receptor-mediated apoptosis has emerged as an effective strategy for cancer therapy. However, certain types of cancer cells are intrinsically resistant to death receptor-mediated apoptosis. In an effort to identify agents that can sensitize cancer cells to death receptor-induced apop...

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Detalhes bibliográficos
Main Authors: Raja, Shruti M., Chen, Shuzhen, Yue, Ping, Acker, Timothy M., Lefkove, Benjamin, Arbiser, Jack L., Khuri, Fadlo R., Sun, Shi-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756752/
https://ncbi.nlm.nih.gov/pubmed/18645030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2409
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