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Probing the Allosteric Modulator Binding Site of GluR2 with Thiazide Derivatives
Ionotropic glutamate receptors mediate the majority of vertebrate excitatory synaptic transmission and are therapeutic targets for cognitive enhancement and treatment of schizophrenia. The binding domains of these tetrameric receptors consist of two dimers, and the dissociation of the dimer interfac...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756660/ https://ncbi.nlm.nih.gov/pubmed/19673491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901127s |
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