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Formulating a Sulfonated Anti-Viral Dendrimer in a Vaginal Microbicidal Gel having Dual Mechanisms of Action

SPL7013 is the sodium salt of a sulfonated dendrimer that has potent antiviral properties. VivaGel®, a topical gel containing 3% w/w SPL7013, has been shown to be safe and well-tolerated in human clinical studies. BufferGel® is a Carbopol®-based acidic buffering gel that enhances the natural protect...

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Bibliografiske detaljer
Main Authors: Mumper, Russell J., Bell, Michael A., Worthen, David R., Cone, Richard A., Lewis, Gareth R., Moench, Thomas R.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756599/
https://ncbi.nlm.nih.gov/pubmed/19040181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03639040802488097
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