Structure Activity Relationship of Dendrimer Microbicides with Dual Action Antiviral Activity

BACKGROUND: Topical microbicides, used by women to prevent the transmission of HIV and other sexually transmitted infections are urgently required. Dendrimers are highly branched nanoparticles being developed as microbicides. However, the anti-HIV and HSV structure-activity relationship of dendrimer...

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Autores principales: Tyssen, David, Henderson, Scott A., Johnson, Adam, Sterjovski, Jasminka, Moore, Katie, La, Jennifer, Zanin, Mark, Sonza, Secondo, Karellas, Peter, Giannis, Michael P., Krippner, Guy, Wesselingh, Steve, McCarthy, Tom, Gorry, Paul R., Ramsland, Paul A., Cone, Richard, Paull, Jeremy R. A., Lewis, Gareth R., Tachedjian, Gilda
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925893/
https://ncbi.nlm.nih.gov/pubmed/20808791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012309
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