Integration of Genomic and Genetic Approaches Implicates IREB2 as a COPD Susceptibility Gene

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death worldwide and is influenced by both genetic determinants and smoking. We identified genomic regions from 56 lung-tissue gene-expression microarrays and used them to select 889 SNPs to be tested for association with COP...

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Hauptverfasser: DeMeo, Dawn L., Mariani, Thomas, Bhattacharya, Soumyaroop, Srisuma, Sorachai, Lange, Christoph, Litonjua, Augusto, Bueno, Raphael, Pillai, Sreekumar G., Lomas, David A., Sparrow, David, Shapiro, Steven D., Criner, Gerard J., Kim, Hong P., Chen, Zhihua, Choi, Augustine M.K., Reilly, John, Silverman, Edwin K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756547/
https://ncbi.nlm.nih.gov/pubmed/19800047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2009.09.004
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