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“On Trk” - the TrkB signal transduction pathway is an increasingly important target in cancer biology

In the beginning - Trk was an oncogene. Yet Neurotrophin-Trk signaling came to pre-eminence in the field of neurobiology. Now it is appreciated that Trks regulate important processes in non-neuronal cells and, in addition to their impact on tumors of neural origin, may contribute to the pathogenesis...

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Main Authors: Thiele, Carol J., Li, Zhijie, McKee, Amy E.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756331/
https://ncbi.nlm.nih.gov/pubmed/19755385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0651
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