microRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes

microRNA-34a (miR-34a) is a transcriptional target of p53 that is down-regulated in some cancer cell lines. We studied the expression, targets and functional effects of miR-34a in brain tumor cells and human gliomas. Transfection of miR-34a down-regulated c-Met in human glioma and medulloblastoma ce...

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Hauptverfasser: Li, Yunqing, Guessous, Fadila, Zhang, Ying, DiPierro, Charles, Kefas, Benjamin, Johnson, Elizabeth, Marcinkiewicz, Lukasz, Jiang, Jinmai, Yang, Yanzhi, Schmittgen, Thomas D., Lopes, Beatriz, Schiff, David, Purow, Benjamin, Abounader, Roger
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756313/
https://ncbi.nlm.nih.gov/pubmed/19773441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0529
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