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Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines

Heparan sulfate binds to and regulates many inflammatory mediators in vitro, suggesting that it serves an important role in directing the progression and outcome of inflammatory responses in vivo. Here, we evaluated the role of syndecan-1, a major heparan sulfate proteoglycan, in modulating multiorg...

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Библиографические подробности
Главные авторы: Hayashida, Kazutaka, Parks, William C., Park, Pyong Woo
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756208/
https://ncbi.nlm.nih.gov/pubmed/19638625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-204966
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