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Rho GTPase Cdc42 is essential for B-lymphocyte development and activation

Cdc42 is a member of the Rho GTPase family that has been implicated in several cell functions including proliferation and migration, but its physiologic role needs to be dissected in each cell type. We achieved B-cell and hematopoietic stem cell deletion of Cdc42 by conditional gene targeting in mic...

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Autori principali: Guo, Fukun, Velu, Chinavenmeni S., Grimes, H. Leighton, Zheng, Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756201/
https://ncbi.nlm.nih.gov/pubmed/19671922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-04-214676
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