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Distinct spatio-temporal Ca(2+) signaling elicited by integrin α2β1 and glycoprotein VI under flow
We studied how integrin α2β1 and glycoprotein VI (GPVI) contribute to collagen-induced platelet activation under flow conditions by evaluating stable adhesion and intracellular Ca(2+) concentration ([Ca(2+)](i)) of FLUO 3-AM–labeled platelets perfused over acid-soluble type I or microfibrillar type...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756134/ https://ncbi.nlm.nih.gov/pubmed/19622836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-193490 |
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