The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels

OBJECTIVE: Activating Transcription Factor 6 (ATF6) is a sensor of the endoplasmic reticulum stress response and regulates expression of several key lipogenic genes. We utilized a two-stage design to investigate whether ATF6 polymorphisms are associated with lipids in subjects at increased risk for...

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Main Authors: Meex, Steven J.R., Weissglas-Volkov, Daphna, van der Kallen, Carla J.H., Thuerauf, Donna J., van Greevenbroek, Marleen M.J., Schalkwijk, Casper G., Stehouwer, Coen D.A., Feskens, Edith J.M., Heldens, Lonneke, Ayoubi, Torik A., Hofker, Marten H., Wouters, Bradly G., Vlietinck, Robert, Sinsheimer, Janet S., Taskinen, Marja-Riitta, Kuusisto, Johanna, Laakso, Markku, de Bruin, Tjerk W.A., Pajukanta, Päivi, Glembotski, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756089/
https://ncbi.nlm.nih.gov/pubmed/19667116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.180240
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