Requirement of Myosin Vb·Rab11a·Rab11-FIP2 Complex in Cholesterol-regulated Translocation of NPC1L1 to the Cell Surface

Niemann-Pick C1-like 1 (NPC1L1) plays a critical role in the enterohepatic absorption of free cholesterol. Cellular cholesterol depletion induces the transport of NPC1L1 from the endocytic recycling compartment to the plasma membrane (PM), and cholesterol replenishment causes the internalization of...

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Autori principali: Chu, Bei-Bei, Ge, Liang, Xie, Chang, Zhao, Yang, Miao, Hong-Hua, Wang, Jing, Li, Bo-Liang, Song, Bao-Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755969/
https://ncbi.nlm.nih.gov/pubmed/19542231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.034355
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