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Sustained Receptor Stimulation Leads to Sequestration of Recycling Endosomes in a Classical Protein Kinase C- and Phospholipase D-dependent Manner

Considerable insight has been garnered on initial mechanisms of endocytosis of plasma membrane proteins and their subsequent trafficking through the endosomal compartment. It is also well established that ligand stimulation of many plasma membrane receptors leads to their internalization. However, s...

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Auteurs principaux: Idkowiak-Baldys, Jolanta, Baldys, Aleksander, Raymond, John R., Hannun, Yusuf A.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755955/
https://ncbi.nlm.nih.gov/pubmed/19525236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.026765
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