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Bile Acid-induced Epidermal Growth Factor Receptor Activation in Quiescent Rat Hepatic Stellate Cells Can Trigger Both Proliferation and Apoptosis

Bile acids have been reported to induce epidermal growth factor receptor (EGFR) activation and subsequent proliferation of activated hepatic stellate cells (HSC), but the underlying mechanisms and whether quiescent HSC are also a target for bile acid-induced proliferation or apoptosis remained uncle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sommerfeld, Annika, Reinehr, Roland, Häussinger, Dieter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755942/
https://ncbi.nlm.nih.gov/pubmed/19553664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.005355
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