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Opposing Role of Condensin and Radiation-sensitive Gene RAD52 in Ribosomal DNA Stability Regulation

Blocking target of rapamycin signaling by starvation or rapamycin inhibits ribosomal DNA (rDNA) transcription and causes condensin-mediated rDNA condensation and nucleolar contraction. In the absence of condensin, however, repression of rDNA transcription leads to rDNA instability and elevated level...

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Autors principals: Tsang, Chi Kwan, Zheng, X. F. Steven
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755915/
https://ncbi.nlm.nih.gov/pubmed/19520859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.031302
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