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Unidirectional Cre-mediated genetic inversion in mice using the mutant loxP pair lox66/lox71
The Cre/loxP recombination system is a commonly used tool to alter the mouse genome in a conditional manner by deletion or inversion of loxP-flanked DNA segments. While Cre-mediated deletion is essentially unidirectional, inversion is reversible and therefore does not allow the stable alteration of...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC275577/ https://ncbi.nlm.nih.gov/pubmed/14602933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gng140 |
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