Increased Intraocular Insulin-like Growth Factor-I Triggers Blood-Retinal Barrier Breakdown

Blood-retinal barrier (BRB) breakdown is a key event in diabetic retinopathy and other ocular disorders that leads to increased retinal vascular permeability. This causes edema and tissue damage resulting in visual impairment. Insulin-like growth factor-I (IGF-I) is involved in these processes, alth...

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Detalhes bibliográficos
Main Authors: Haurigot, Virginia, Villacampa, Pilar, Ribera, Albert, Llombart, Cristina, Bosch, Assumpcio, Nacher, Victor, Ramos, David, Ayuso, Eduard, Segovia, José C., Bueren, Juan A., Ruberte, Jesus, Bosch, Fatima
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755703/
https://ncbi.nlm.nih.gov/pubmed/19473988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.014787
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