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Kissing complex-mediated dimerisation of HIV-1 RNA: coupling extended duplex formation to ribozyme cleavage

Initiation of retroviral genomic RNA dimerisation is mediated by the mutual interaction of the dimerisation initiation site (DIS) stem–loops near to the 5′ end of the RNA. This process is thought to involve formation of a transient ‘kissing’ complex over the self-complementary loop bases, which then...

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Detalhes bibliográficos
Main Authors: Windbichler, Nikolai, Werner, Michael, Schroeder, Renée
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC275567/
https://ncbi.nlm.nih.gov/pubmed/14602899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg873
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