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Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice

Diabetes may adversely affect cognitive function, but the underlying mechanisms are unknown. To investigate whether manipulations that enhance neurotrophin levels will also restore neuronal structure and function in diabetes, we examined the effects of wheel running and dietary energy restriction on...

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Autori principali: Stranahan, Alexis M., Lee, Kim, Martin, Bronwen, Maudsley, Stuart, Golden, Erin, Cutler, Roy G., Mattson, Mark P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755651/
https://ncbi.nlm.nih.gov/pubmed/19280661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.20577
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