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Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice

Diabetes may adversely affect cognitive function, but the underlying mechanisms are unknown. To investigate whether manipulations that enhance neurotrophin levels will also restore neuronal structure and function in diabetes, we examined the effects of wheel running and dietary energy restriction on...

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Detalhes bibliográficos
Main Authors: Stranahan, Alexis M., Lee, Kim, Martin, Bronwen, Maudsley, Stuart, Golden, Erin, Cutler, Roy G., Mattson, Mark P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755651/
https://ncbi.nlm.nih.gov/pubmed/19280661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.20577
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