Differentiation of lung adenocarcinoma, pleural mesothelioma, and non-malignant pulmonary tissues using DNA methylation profiles

Pathologic differentiation of tissue of origin in tumors found in the lung can be challenging, with differentiation of mesothelioma and lung adenocarcinoma emblematic of this problem. Indeed, proper classification is essential for determination of treatment regimen for these diseases, making accurat...

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Hauptverfasser: Christensen, Brock C., Marsit, Carmen J., Houseman, E Andres, Godleski, John J., Longacker, Jennifer L., Zheng, Shichun, Yeh, Ru-Fang, Wrensch, Margaret R., Wiemels, Joseph L., Karagas, Margaret R., Bueno, Raphael, Sugarbaker, David J., Nelson, Heather H., Wiencke, John K., Kelsey, Karl T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755616/
https://ncbi.nlm.nih.gov/pubmed/19638575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1073
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