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Central leptin gene therapy ameliorates diabetes type 1 and 2 through two independent hypothalamic relays: a benefit beyond weight and appetite regulation
Although its role in energy homeostasis is firmly established, the evidence accumulated over a decade linking the adipocyte leptin -hypothalamus axis in the pathogenesis of diabetes mellitus has received little attention in the contemporary thinking. In this context various lines of evidence are col...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755606/ https://ncbi.nlm.nih.gov/pubmed/19647774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2009.07.021 |
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