Characterization of cytoplasmic caspase-2 activation by induced proximity

Caspase-2 is an initiator caspase, activated in response to heat shock and other stressors that induce apoptosis. Activation of caspase-2 requires induced proximity resulting after recruitment to caspase-2 activation complexes, such as the PIDDosome. We have adapted bimolecular fluorescence compleme...

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Autori principali: Bouchier-Hayes, Lisa, Oberst, Andrew, McStay, Gavin P., Connell, Samuel, Tait, Stephen W.G., Dillon, Christopher P., Flanagan, Jonathan M., Beere, Helen M., Green, Douglas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755603/
https://ncbi.nlm.nih.gov/pubmed/19782032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.07.023
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