L-Asparaginase Encapsulated Intact Erythrocytes for Treatment of Acute Lymphoblastic Leukemia (ALL)

As a primary drug for the treatment of acute lymphoblastic leukemia (ALL), encapsulation of L-asparaginase (ASNase) into red blood cells (RBC) has been popular to circumvent immunogenicity from the exogenous protein. Unlike existing methods that perturbs RBC membranes, we introduce a novel method of...

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Autors principals: Kwon, Young Min, Chung, Hee Sun, Moon, Cheol, Yockman, James, Park, Yoon Jeong, Gitlin, Scott D., David, Allan E., Yang, Victor C.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755588/
https://ncbi.nlm.nih.gov/pubmed/19577600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.06.027
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