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Erythrocyte encapsulated l-asparaginase (GRASPA) in acute leukemia

l-asparaginase, an enzyme originally derived from Escherichia coli, represents a major drug in the treatment of acute lymphoblastic leukemia. However, the occurrence of major adverse effects often leads to early withdrawal of the enzyme. Main side effects include immune-allergic reactions, coagulopa...

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Detalhes bibliográficos
Publicado no:Int J Hematol Oncol
Main Authors: Thomas, Xavier, Le Jeune, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172001/
https://ncbi.nlm.nih.gov/pubmed/30302200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/ijh-2016-0002
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