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Human 3β-Hydroxysteroid Dehydrogenase Types 1 and 2: Gene Sequence Variation and Functional Genomics
The 3β-hydroxysteroid dehydrogenase/Δ(5)-Δ(4) isomerase isoenzymes 1 and 2 (HSD3B1 and HSD3B2) are membrane-bound enzymes that play essential roles in the biosynthesis of steroid hormones. Therefore, variation in the HSD3B1 and HSD3B2 genes might play a role in the pathophysiology of steroid hormone...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755580/ https://ncbi.nlm.nih.gov/pubmed/17689071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2007.03.037 |
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