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Common sequence variants on 20q11.22 confer melanoma susceptibility

We conducted a genome-wide association pooling study for cutaneous melanoma and performed validation in samples totalling 2019 cases and 2105 controls. Using pooling we identified a novel melanoma risk locus on chromosome 20 (rs910873, rs1885120), with replication in two further samples (combined P...

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Bibliographische Detailangaben
Hauptverfasser: Brown, Kevin M., MacGregor, Stuart, Montgomery, Grant W., Craig, David W., Zhao, Zhen Zhen, Iyadurai, Kelly, Henders, Anjali, Homer, Nils, Campbell, Megan, Stark, Mitchell, Thomas, Shane, Schmid, Helen, Holland, Elizabeth A, Gillanders, Elizabeth M., Duffy, David L., Maskiell, Judith A., Jetann, Jodie, Ferguson, Megan, Stephan, Dietrich A., Cust, Anne E., Whiteman, David, Green, Adele, Olsson, Håkan, Puig, Susana, Ghiorzo, Paola, Hansson, Johan, Demenais, Florence, Goldstein, Alisa M., Gruis, Nelleke A., Elder, David E., Bishop, Julia Newton, Kefford, Richard F., Giles, Graham G., Armstrong, Bruce K., Aitken, Joanne F., Hopper, John L., Martin, Nicholas G., Trent, Jeffrey M., Mann, Graham J., Hayward, Nicholas K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755512/
https://ncbi.nlm.nih.gov/pubmed/18488026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.163
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