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Common sequence variants on 20q11.22 confer melanoma susceptibility

We conducted a genome-wide association pooling study for cutaneous melanoma and performed validation in samples totalling 2019 cases and 2105 controls. Using pooling we identified a novel melanoma risk locus on chromosome 20 (rs910873, rs1885120), with replication in two further samples (combined P...

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Detalhes bibliográficos
Main Authors: Brown, Kevin M., MacGregor, Stuart, Montgomery, Grant W., Craig, David W., Zhao, Zhen Zhen, Iyadurai, Kelly, Henders, Anjali, Homer, Nils, Campbell, Megan, Stark, Mitchell, Thomas, Shane, Schmid, Helen, Holland, Elizabeth A, Gillanders, Elizabeth M., Duffy, David L., Maskiell, Judith A., Jetann, Jodie, Ferguson, Megan, Stephan, Dietrich A., Cust, Anne E., Whiteman, David, Green, Adele, Olsson, Håkan, Puig, Susana, Ghiorzo, Paola, Hansson, Johan, Demenais, Florence, Goldstein, Alisa M., Gruis, Nelleke A., Elder, David E., Bishop, Julia Newton, Kefford, Richard F., Giles, Graham G., Armstrong, Bruce K., Aitken, Joanne F., Hopper, John L., Martin, Nicholas G., Trent, Jeffrey M., Mann, Graham J., Hayward, Nicholas K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755512/
https://ncbi.nlm.nih.gov/pubmed/18488026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.163
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