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Testing the in vivo role of protein kinase C and c-fos in neurite outgrowth by microinjection of antibodies into PC12 cells.

To define the molecular bases of growth factor-induced signal transduction pathways, antibodies known to block the activity of either protein kinase C (PKC) or the fos protein were introduced into PC12 cells by microinjection. The antibody against PKC significantly inhibited neurite outgrowth when s...

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Detaylı Bibliyografya
Yayımlandı:Mol Biol Cell
Asıl Yazarlar: Altin, J G, Wetts, R, Riabowol, K T, Bradshaw, R A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Cell Biology 1992
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1627832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.3.3.323
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