The paraoxonase (PON1) Q192R polymorphism is not associated with poor health status or depression in the ELSA or InCHIANTI studies

Background The human paraoxonase (PON1) protein detoxifies certain organophosphates, and the PON1 Q192R polymorphism (rs662) affects PON1 activity. Groups with higher dose exposure to organophosphate sheep dips or first Gulf War nerve toxins reported poorer health if they had 192R, and these associa...

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Autores principales: Rice, Neil E, Bandinelli, Stefania, Corsi, Anna Maria, Ferrucci, Luigi, Guralnik, Jack M, Miller, Michelle A, Kumari, Meena, Murray, Anna, Frayling, Tim M, Melzer, David
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2009
Materias:
Genetic Epidemiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755129/
https://ncbi.nlm.nih.gov/pubmed/19651761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyp265
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