The paraoxonase (PON1) Q192R polymorphism is not associated with poor health status or depression in the ELSA or InCHIANTI studies

Background The human paraoxonase (PON1) protein detoxifies certain organophosphates, and the PON1 Q192R polymorphism (rs662) affects PON1 activity. Groups with higher dose exposure to organophosphate sheep dips or first Gulf War nerve toxins reported poorer health if they had 192R, and these associa...

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Autors principals: Rice, Neil E, Bandinelli, Stefania, Corsi, Anna Maria, Ferrucci, Luigi, Guralnik, Jack M, Miller, Michelle A, Kumari, Meena, Murray, Anna, Frayling, Tim M, Melzer, David
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
Matèries:
Genetic Epidemiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755129/
https://ncbi.nlm.nih.gov/pubmed/19651761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyp265
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