Noncovalent Complexes of APS Reductase from M. Tuberculosis: Delineating a Mechanistic Model using ESI-FTICR MS

ESI-FTICR MS was utilized to characterize a 4Fe-4S containing protein Mycobacterium tuberculosis APS reductase. This enzyme catalyzes the reduction of APS to sulfite and AMP with reducing equivalents from the protein cofactor, thioredoxin. Under nondenaturing conditions, a distribution of the apopro...

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Hauptverfasser: Gao, Hong, Carroll, Kate S., Chen, Huiyi, Bertozzi, Carolyn R., Leary, Julie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755055/
https://ncbi.nlm.nih.gov/pubmed/17023175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2006.08.010
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