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Insulin Acts through FOXO3a to Activate Transcription of Plasminogen Activator Inhibitor Type 1
Plasminogen activator inhibitor-1 (PAI-1) is an important regulator of fibrinolysis. PAI-1 levels are elevated in type 2 diabetes, and this elevation correlates with macro- and microvascular complications of diabetes. However, the mechanistic link between insulin and up-regulation of PAI-1 is unclea...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754891/ https://ncbi.nlm.nih.gov/pubmed/19608644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0421 |
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