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Peroxisome Proliferator-Activated Receptor γ and Retinoid X Receptor transcription factors are released from activated human platelets and shed in microparticles

Peroxisome proliferator-activated receptor γ (PPARγ) and its ligands are important regulators of lipid metabolism, inflammation, and diabetes. We previously demonstrated that anucleate human platelets express the transcription factor PPARγ and that PPARγ ligands blunt platelet activation. To further...

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Detalhes bibliográficos
Main Authors: Ray, D. M., Spinelli, S. L., Pollock, S. J., Murant, T. I., O’Brien, J. J., Blumberg, N., Francis, C. W., Taubman, M. B., Phipps, R. P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754860/
https://ncbi.nlm.nih.gov/pubmed/18217139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH07-05-0328
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