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A small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion
Heat shock protein 90 is a molecular chaperone that maintains function of numerous intracellular signaling nodes utilized by cancer cells for proliferation and survival. Hsp90 is also detected on the plasma membrane of tumor cells and its expression has been suggested to correlate with metastatic po...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754825/ https://ncbi.nlm.nih.gov/pubmed/17968312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210897 |
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