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How Mitogen-Activated Protein Kinases Recognize and Phosphorylate Their Targets: A QM/MM Study

Mitogen-activated protein kinase (MAPK) signaling pathways play an essential role in the transduction of environmental stimuli to the nucleus, thereby regulating a variety of cellular processes, including cell proliferation, differentiation and programmed cell death. The components of the MAPK extra...

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Библиографические подробности
Главные авторы: Turjanski, Adrian Gustavo, Hummer, Gerhard, Gutkind, J. Silvio
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754815/
https://ncbi.nlm.nih.gov/pubmed/19361221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8071995
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