Structural Basis for α-Conotoxin Potency and Selectivity

Parkinson’s disease is a debilitating movement disorder characterized by altered levels of α(6)β(2) nicotinic acetylcholine receptors (nAChRs) localized on presynaptic striatal catecholaminergic neurons. α-Conotoxin MII (α-CTx MII) is a highly useful ligand to probe α(6)β(2) nAChRs structure and fun...

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Detalhes bibliográficos
Main Authors: Turner, Matt, Eidemiller, Seth, Martin, Bryan, Narver, Andrew, Marshall, Joshua, Zemp, Logan, Cornell, Kenneth A., McIntosh, J. Michael, McDougal, Owen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754775/
https://ncbi.nlm.nih.gov/pubmed/19628399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.07.005
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