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Stabilized β-catenin in lung epithelial cells changes cell fate and leads to tracheal & bronchial polyposis
The precise mechanisms by which β-catenin controls morphogenesis and cell differentiation remain largely unknown. Using embryonic lung development as a model, we deleted exon 3 of β-catenin via Nkx2.1-cre in the Catnb[+/lox(ex3)] mice and studied its impact on epithelial morphogenesis. Robust select...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754730/ https://ncbi.nlm.nih.gov/pubmed/19631635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.07.021 |
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