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Novel Biodegradable Poly(disulfide amine)s for Gene Delivery with High Efficiency and Low Cytotoxicity

Novel biodegradable poly(disulfide amine)s with defined structure, high transfection efficiency, and low cytotoxicity were designed and synthesized as nonviral gene delivery carriers. Michael addition between N,N′-cystaminebisacrylamide (CBA) and three N-Boc protected diamines (N-Boc-1,2-diaminoetha...

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Main Authors: Ou, Mei, Wang, Xu-Li, Xu, Rongzuo, Chang, Chien-Wen, Bull, David A., Kim, Sung Wan
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754712/
https://ncbi.nlm.nih.gov/pubmed/18314939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc700397x
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